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Alpha GPC (50%) – Powder, 50 grams

Alpha GPC (L-alpha-glycerylphosphorylcholine) is a naturally occurring choline-containing phospholipid metabolite that serves as a highly bioavailable precursor in cholinergic signaling pathways.

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Alpha GPC (L-alpha-glycerylphosphorylcholine) is a naturally occurring choline-containing phospholipid metabolite that serves as a highly bioavailable precursor in cholinergic signaling pathways. Experimental investigations have examined its role in acetylcholine-associated neurotransmission, choline transport mechanisms, phospholipid metabolism, and membrane phospholipid biosynthesis.

Alpha GPC has also been studied in relation to cholinergic receptor signaling, neurotransmitter precursor dynamics, and molecular processes governing phosphatidylcholine turnover.

These characteristics make it a valuable research tool for studies of cholinergic neurotransmission, acetylcholine biosynthesis pathways, phospholipid metabolism, nootropic mechanism investigation, and membrane-associated signaling systems.

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3D Molecular Structure

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Chemical Formula C8H20NO6P
Synonyms L-Alpha-Glycerylphosphorylcholine, Choline Alfoscerate, Alpha-GPC
Molar Mass 257.22 g/mol
CAS Number 28319-77-9
PubChem CID 657272
Total Compound Content 50 g (50% active Alpha GPC by weight)
Shelf Life 36 months
Alpha GPC (L-alpha-glycerylphosphorylcholine) is a choline-containing phospholipid metabolite that serves as a precursor within cholinergic signaling and phospholipid metabolic pathways. Experimental investigations have examined its role in acetylcholine biosynthesis, choline transport mechanisms, phosphatidylcholine metabolism, and membrane phospholipid turnover. Alpha GPC has also been studied in relation to cholinergic neurotransmission, neurotransmitter precursor dynamics, and molecular processes governing phospholipid-associated signaling systems. The 50% format consists of Alpha GPC stabilized within a carrier matrix to improve physicochemical handling characteristics while maintaining defined active content for research applications. These properties make Alpha GPC a valuable research tool for studies of cholinergic pathway pharmacology, acetylcholine-associated signaling, phospholipid metabolism, nootropic mechanism investigation, and membrane-associated regulatory processes. Supplied as 50% active Alpha GPC by weight (25 g active per 50 g). Independently third-party HPLC-tested; COA available per batch.

Every batch is independently lab tested for identity, purity and potency. View our lab testing program →

Why is the 50% form of Alpha GPC commonly used rather than pure Alpha GPC powder?

Pure Alpha GPC is highly hygroscopic and readily absorbs atmospheric moisture, making it difficult to handle as a free-flowing powder. The 50% format incorporates a carrier matrix that improves physicochemical stability, powder consistency, and handling characteristics while maintaining a defined active content.

As a result, the 50% form is widely utilized in analytical, formulation, and laboratory research applications requiring reliable powder properties and standardized composition.

How does Alpha GPC differ from CDP-choline (citicoline) as a cholinergic research compound?

Alpha GPC and CDP-choline are both choline-containing compounds investigated in cholinergic signaling research, but they differ in their metabolic pathways and molecular composition.

Alpha GPC functions as a glycerophosphocholine-derived precursor within cholinergic and phospholipid metabolic systems, whereas CDP-choline contains a cytidine-linked structure that participates in distinct biochemical pathways. These differences make both compounds valuable tools for comparative studies of choline metabolism, phospholipid biosynthesis, and cholinergic signaling mechanisms.

What are the primary research applications of Alpha GPC?

Alpha GPC is widely used in studies of cholinergic neurotransmission, acetylcholine biosynthesis pathways, phosphatidylcholine metabolism, membrane phospholipid turnover, and neurotransmitter precursor dynamics.

Experimental investigations have examined its role in choline transport mechanisms, phospholipid-associated signaling systems, and molecular processes governing cholinergic pathway regulation. These characteristics make Alpha GPC a valuable research tool for mechanistic studies of cholinergic pharmacology, phospholipid metabolism, and membrane-associated regulatory networks.

Customer Reviews (9)

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Mike A

I placed my order in December 0f 2022 and still haven't received my package. I've also made three request for a refund , just to have them go unanswered. It's now April 14 2023 and I'm still waiting for a response to my refund request. So for future customers I would advise not dealing with this company in anyway. I'm sure this review won't be posted where anyone will read it.

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Love their products, can't beat the prices and I love that they include a generous amount of free samples. Delivery is always fast, never had an issue

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Superb service and product quality. I’ll be a repeat customer for sure.

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